Class: Ertapenem

ATCID "J01DH03" ()
CID "C1120106" ()
SID "396346003" ()
definition "A 1-beta-methyl carbapenem and broad-spectrum beta-lactam antibiotic with bactericidal property. Ertapenem binds to penicillin binding proteins (PBPs) located on the bacterial cell wall, in particular PBPs 2 and 3, thereby inhibiting the final transpeptidation step in the synthesis of peptidoglycan, an essential component of the bacterial cell wall. Inhibition results in a weakening and subsequent lysis of the cell wall leading to cell death of Gram-positive and Gram-negative aerobic and anaerobic pathogens. This agent is stable against hydrolysis by a variety of beta-lactamases, including penicillinases, cephalosporinases and extended-spectrum beta-lactamases. (definition derived from NCI)" ()
label "ertapenem" ()
seeAlso "385574002" ()

http://purl.org/imbi/dco/dco#Ertapenem